ABSTRACT
Background: The novel coronavirus disease caused numerous hospitalizations around the world. Because of constant changes in protocols and the limited number of available beds and manpower, newborn admissions were affected. The objective of this study is to determine the newborn census and neonatal outcome in the University of the East Ramon Magsaysay (UERM) Memorial Medical Center a year prior to the pandemic and during the pandemic. Methods: The study utilized a descriptive, cross sectional, analytical approach. A chart review of all newborns delivered from March 2019 to March 2021 was done to determine the number of admissions and neonatal outcomes. To determine the statistical differences between the means of the pre-pandemic and pandemic variables, paired t-test was used. The data was then analyzed using Minitab statistical software. Results: There was a significant difference between the number of newborn admissions prior to the pandemic and during the pandemic. From the infants born during the pandemic, 1.5% were born to COVID-19 suspect mothers and 0.9% were born to COVID-19 confirmed mothers. None of the infants of COVID-19 suspect and confirmed mothers tested positive for SARS-CoV-2, but one of each were treated for neonatal pneumonia. One newborn had a positive SARS-CoV-2 IgG antibody. Conclusions: The study showed a significant difference in the number of newborn admissions in the UERM Memorial Medical Center prior to the pandemic and during the pandemic. It also showed that the infants born to COVID-19 suspect and confirmed mothers were all born term, and had good neonatal outcomes.
ABSTRACT
Aim: To make a comparative analysis of causes and rates of early neonatal mortality in the Russian Federation in 2019 and 2020. Materials and methods: This study was based on the analysis of statistical forms А-05 of the Federal State Statistics Service (Rosstat) for the years 2019–2020. These forms included medical records of perinatal deaths related to stillbirths. Stillbirth rates were calculated as the ratio of stillbirths to the total number of babies born alive and dead multiplied by 1000. Results: In 2020, the number of babies born alive decreased by 7.6%, and the number of babies born dead increased by 1.12% versus the data reported in 2019. In 2020, the rate of stillbirth (5.67‰) increased by 4.2% versus the rate in 2019 (5.44‰). Most of all, the increase in stillbirths was noted in the South and Siberian Federal Districts. In general, the most common causes of stillbirths in the Russian Federation were respiratory disorders: the number of antenatal hypoxia was 78.2 (80.5%) and fetal intrapartum hypoxia was 6.7 (5.0%) of total number of stillbirths in 2019 and 2020, respectively. The proportion of congenital anomalies as the main disease was 6.7 (5.4%) of total number of stillbirths in 2019 and 2020, respectively. It was noted, that the number of stillborn babies with unknown causes of death increased by 52.2% in 2020 (4.7% of total number of stillborn babies) versus 2019 (3.1% of total number of stillborn babies)). Significant differences between the rates of major diseases that caused stillbirths were registered in different Federal Districts of the Russian Federation. Conclusion: According to Rosstat data, in 2020 (due to COVID-19 pandemic), the absolute number of babies born dead increased by 1.1% and the rate of stillbirths increased by 4.2% compared to 2019. Increased proportion of respiratory diseases, in particular, antenatal hypoxia and congenital pneumonia, reflects the direct and indirect effects of SARS-CoV-2 infection.
ABSTRACT
BACKGROUND: Pneumopericardium (PPC) is one of the rarest pulmonary air leak syndromes, but the incidence is the highest in the neonatal period. Risk factors include premature infants with respiratory distress (RD) syndrome, receiving active resuscitation, meconium aspiration syndrome, and aggressive mechanical ventilation. Several cases have also been reported related to COVID-19. CASE PRESENTATION: We report a case of a female newborn with a birth weight of 3300 grams a COVID-19 confirmed 35-year-old G3P2A0 mother. The baby was not crying at born and the amniotic fluid was stained green. The baby experienced RD and was intubated. A babygram was performed at the age of 5 h with the impression of a too deep endotracheal tube, neonatal pneumonia, and PPC. COVID-19 RT-PCR examination of the baby was positive. There were no signs of cardiac tamponade, so it was decided to take conservative and supportive management. CONCLUSION: Resolution of PPC was found on repeated babygram 26 h later. The baby was then discharged after 19 days of treatment.
ABSTRACT
BACKGROUND: Compared with Severe Acute Respiratory Syndrome (SARS) and Middle East Respiratory Syndrome (MERS), Corona Virus Disease 2019(COVID-19) spread more rapidly and widely. The population was generally susceptible. However, reports on pregnant women infected with SARS-CoV-2 were very limited. By sharing the clinical characteristics, treatments and outcomes of 18 patients with COVID-19 during late pregnancy, we hope to provide some references for obstetric treatment and management. METHODS: A total of 18 patients with COVID-19 treated at Renmin Hospital of Wuhan University were collected. The epidemiological characteristics, clinical manifestations, laboratory tests, chest CT and pregnancy outcomes were performed for analysis. RESULTS: 1. 18 cases of late pregnancy infected with SARS-CoV-2 pneumonia were delivered at 35 + 5 weeks to 41 weeks. According to the clinical classification of COVID-19, 1 case was mild type, 16 cases were ordinary type, and 1 case was severe type. 2. According to imaging examinations: 15 (83%) cases showed unilateral or bilateral pneumonia, 2 (11%) cases had pulmonary infection with pleural effusion, and 1 (6%) case had no abnormal imaging changes. 8 (44%) cases were positive and 10 (56%) cases were negative for nasopharyngeal-swab tests of SARS-CoV-2. 3. Among the 18 newborns, there were 3 (17%) premature infants, 1 (6%) case of mild asphyxia, 5 (28%) cases of bacterial pneumonia, 1 (6%) case of gastrointestinal bleeding, 1 (6%) case of necrotizing enteritis, 2 (11%) cases of hyperbilirubinemia and 1 (6%) case of diarrhea. All the newborns were negative for the first throat swab test of SARS-CoV-2 after birth. 4. Follow-up to Mar 7, 2020, no maternal and neonatal deaths occurred. CONCLUSIONS: The majority of patients in late term pregnancy with COVID-19 were of ordinary type, and they were less likely to develop into critical pneumonia after early isolation and antiviral treatment. Vertical transmission of SARS-CoV-2 was not detected, but the proportion of neonatal bacterial pneumonia was higher than other neonatal diseases in newborns.